李明珠

   

　　李明珠 女，1984年10月生，博士研究生，副教授，研究生导师

　　研究方向

　　水产动物营养与饲料学

　　学习经历

　　博士：2010.9-2013.7，中国海洋大学，水产养殖专业

　　硕士：2007.9-2010.7，中国海洋大学，动物学专业

　　学士：2004.9-2007.7，青岛农业大学，生物技术专业。

　　工作经历

　　2013.10-2014.07 北京奥特奇生物制品有限公司产品技术服务经理

　　2014.07-2024.06 鲁东大学农学院副教授

　　2024.07-今 鲁东大学水产学院副教授

　　科研项目

　　1.主持并完成中国海洋大学海水养殖教育部重点实验室开放基金《高豆粕饲料中添加乙酸钠对大菱鲆免疫功能的影响及机制研究》，8万。

　　2.主持并完成中国海洋大学海水养殖教育部重点实验室开放基金《皱纹盘鲍合成高不饱和脂肪酸的调控机理研究》，8万。

　　3.主持并完成国家自然科学基金青年项目《脂肪酸调控皱纹盘鲍Δ5脂肪酸去饱和酶基因表达的分子机制》，20万。

　　4.主持并完成企业横向合作课题《奇力素对皱纹盘鲍存活、生长和免疫抗病力的影响》，10万。

　　5.主持山东省教学改革面上项目1项，4万，在研。

　　发表论文

　　1.Chen xuyang,chen wei,zhao nannan,shao mingli,zhang yanling,yuan tingzhu,liu kai,li mingzhu*,wang xiaotong.Ppar is a positive transcription factor of theΔ5 fatty acyl desaturase gene in abalone haliotis discus hannai ino[J].Aquaculture Reports,2024,36.

　　2.Mingzhu Li,Zhixu Chen,Ming Li,Jiugang Zhang,Bingqing Xu,Yanyan Yang,Xiangfei Li,Linlin Fan,Baojun Liu,Tao Zheng,,Yan Fang and Fan Li.Integrated assessment of trace elements in a marine ranching area based on multi-species and multi-level biomarkers:a case study in China’s national-level marine ranching demonstration area[J].Frontier in marine science,2024,Front.Mar.Sci.11:1413847.doi:10.3389/fmars.2024.1413847

　　3.Zhang Shujuan,Chen Xuyang,Shao Mingli,Zhang Jingjing,Wang Kai,Lin Gang,Li Mingzhu*.Hepatopancreatic transcriptome profiles reveal the effects of toxic dietary concentrations of selenium on the immunity and growth of juvenile abalone Haliotis discus hannai[J].Aquaculture Reports,2023,28:101449.

　　4.Xiaoli Li,Meiqin Huang,Nan Li,Huaxian Zhao,Yang Pu,Jiongqing Huang,Shu Yang,Xinyi Qin,Ke Dong,Mingzhu Li*,Zhenjun Kang*.Effects of environmental factors on mycoplankton diversity and trophic modes in coastal surface water[J].Ecological Indicators,2023,146:109778.

　　5.Jinzhu Yang,Zhonghao Zhang,Gang Lin,Mingzhu Li,Yanjiao Zhang*,Kangsen Mai.Organic copper promoted copper accumulation and transport,enhanced low temperature tolerance and physiological health of white shrimp(Litopenaeus vannamei Boone,1931)[J].Fish&Shellfish Immunology,2023,132:108459.

　　6.Yan Fang,Xiyun Yang,Shujuan Zhang,Xuyang Chen,Gang Lin,Yuqing Zhang,Mengjiao Wang,Mingzhu Li*.Transcriptome study on immune response against Vibrio parahaemolyticus challenge in gill of abalone Haliotis discus hannai Ino[J].Frontiers in Marine Science,2022,9:956317.

　　7.Jinzhu Yang,Tiantian Wang,Gang Lin,Mingzhu Li,Yanjiao Zhang*,Kangsen Mai.The Assessment of Dietary Organic Zinc on Zinc Homeostasis,Antioxidant Capacity,Immune Response,Glycolysis and Intestinal Microbiota in White Shrimp(Litopenaeus vannamei Boone,1931)[J].Antioxidants,2022,11(8):1492.

　　8.Xiaoxue Meng,Xiyun Yang,Gang Lin,Yan Fang,Zeli Ruan,Mingfang Liu,Guoxu Liu,Mingzhu Li*,Dinglong Yang*.Mannan oligosaccharide increases the growth performance,immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino[J].Fish&shellfish immunology,2019,94:654-660.

　　9.Yaoyao Kong,Shengqiang Li,Mingfang Liu,Chuanwei Yao,Xiyun Yang,Nannan Zhao,Mingzhu Li*.Effect of dietary organic selenium on survival,growth,antioxidation,immunity and gene expressions of selenoproteins in abalone Haliotis discus hannai[J].Aquaculture Research,2019,50(3):847-855.

　　10.Shengqiang Li,Zeli Ruan,Xiyun Yang,Mingzhu Li*,Dinglong Yang*.Immune recognition,antimicrobial and opsonic activities mediated by a sialic acid binding lectin from Ruditapes philippinarum[J].Fish&Shellfish Immunology,2019,93:66-72.

　　11.Shihang Dong,Yanyan Yang,Bo Cheng,Chuanbo Ren,Huawei Zhang,Hua Xu,Na Zhu,Wansheng Wang,Yongjian Dang,Mingzhu Li,Jun Chen,Kai Wang,Libin Zhang,Yan Fang*.Responses of antioxidant defenses in the clam Mactra veneriformis to 2,2′,4,4′tetrabromodiphenyl ether exposure[J].Comparative Biochemistry and Physiology Part C:Toxicology&Pharmacology,2019,217:98-105.

　　12.Songlin Li,Yuhui Yuan,Tianjiao Wang,Wei Xu,Mingzhu Li,Kangsen Mai,Qinghui Ai*.Molecular cloning,functional characterization and nutritional regulation of the putative elongase Elovl5 in the orange-spotted grouper(Epinephelus coioides)[J].PLoS One,2016,11(3):e0150544.

　　13.Yancui Zhao,Lei Yuan,Mingzhu Li,Junli Wan,Yiyan Wang,Hushan Sun.Dietary probiotic Bacillus licheniformis TC22 increases growth,immunity,and disease resistance,against Vibrio splendidus infection in juvenile sea cucumbers Apostichopus japonicus[J].Israeli Journal of Aquaculture–Bamidgeh,2017,1(1),1415.

　　14.Yuyu Wang,Mingzhu Li,Keith Filer,Yan Xue,Qinghui Ai*,Kangsen Mai*.Evaluation of Schizochytrium meal in microdiets of Pacific white shrimp(Litopenaeus vannamei)larvae[J].Aquaculture Research,2016,48(5):2328-2336.

　　15.Yuyu Wang,Mingzhu Li,Keith Filer,Yan Xue,Qinghui Ai*,Kangsen Mai*.Replacement of fish oil with a DHA‐rich Schizochytrium meal on growth performance,activities of digestive enzyme and fatty acid profile of Pacific white shrimp(Litopenaeus vannamei)larvae[J].Aquaculture Nutrition,2017,23(5):1113-1120.

　　16.Mingzhu Li,Kangsen Mai*,Qinghui Ai,Gen He,Wei Xu,Wenbing Zhang,Yanjiao Zhang,Huihui Zhou,Zhiguo Liufu.Effect of dietary lipid on the growth,fatty acid composition andΔ5 Fads expression of abalone(Haliotis discus hannai Ino)hepatopancreas[J].Journal of Ocean University of China,2015,14:317-324.

　　17.Mingzhu Li,Kangsen Mai*,Qinghui Ai,Gen He,Wei Xu,Wenbing Zhang,Yanjiao Zhang,Huihui Zhou.Effects of dietary grape seed oil and linseed oil on growth,muscle fatty acid composition and expression of putativeΔ5 fatty acyl desaturase in abalone Haliotis discus hannai Ino[J].Aquaculture,2013,406:105-114.

　　18.Mingzhu Li,Kangsen Mai*,Gen He,Qinghui Ai,Wenbing Zhang,Wei Xu,Jia Wang,Zhiguo Liufu,Yanjiao Zhang,Huihui Zhou.Characterization of twoΔ5 fatty acyl desaturases in abalone(Haliotis discus hannai Ino)[J].Aquaculture,2013,416:48-56.

　　19.张淑娟,邵明丽,陈旭阳,李明珠*.硒对水产养殖动物的生物学功能和毒性作用及其机理研究进展[J].动物营养学报,2023,35(05):2815-2827.

　　20.李明珠,麦康森*,何艮,艾庆辉,徐玮,张文兵.实时荧光定量PCR检测皱纹盘鲍Δ5脂肪酸去饱和酶基因表达方法的建立及应用[J].水生生物学报,2014,38(02):328-334.

　　21.一种用于提高幼鲍抗病力的饲料及幼鲍饲养方法，CN108294195B[P].2018.国家发明专利

　　22.一种适用于液氮的新型研磨装置，CN208800236U[P].2019.实用新型专利

　　23.一种鲍鱼血细胞抗凝保护剂及其制备方法,CN107988140A[P].2021.国家发明专利

　　24.一种鲍鱼血细胞处理方法，CN108396008A[P].2021.国家发明专利

　　所获奖励

　　指导学生比赛获奖

　　1.2019.11，指导学生刘国旭获第一届全国大学生水产技能大赛“饲料原料辨识与配方制作”项目二等奖，荣获优秀指导教师。

　　2.2023.03，带领学生获“欧贝尔杯”第二届山东省水产类专业实践能力竞赛一等奖，获优秀指导教师称号。

　　3.2023.11，指导学生获“欧倍尔杯”首届高校大学生水产类创新实践能力大赛全国总决赛团队特等奖，三项个人优秀奖，指导学生高法舜获“饲料原料鉴别和配方设计”单项优秀奖，获优秀指导教师称号。

　　教学获奖

　　1.2023.07，获“山东省第十届高校青年教师教学比赛”，三等奖。

　　2.2023.11，获“山东省第十一届高校青年教师教学比赛”校内选拔赛，二等奖。

　　3.2024.01，获批山东省教改面上项目——“四维度”综合推动高等学校课堂教学模式创新改革与实践—以《水产动物营养与饲料学》为例。

　　4.2024.03获“2024年山东省普通高校教师教学创新比赛”校赛，一等奖。

　　5.2024.06，获“山东省第四届全国高校教师教学创新大赛”，二等奖。

　　6.2024.07，获鲁东大学全校优秀共产党员称号。

　　电子邮箱

　　ldulimingzhu@163.com; ava1022@163.com