苏晓磊

　　苏晓磊 男，1994年8月生，博士，讲师，研究生导师　　

　　研究方向

　　鱼类遗传育种

　　主持项目

1. 国家自然科学基金青年基金：海马uevld基因调控肝脏代谢响应低氧分子机制的研究（32402998），2025.1.1-2027.12.31

2. 山东省高等学校优秀”青年创新团队科技计划”：鱼类种质资源开发与利用创新团队（2024KJI021），2025.1.1-2027.12.31

3. 烟台市科技创新发展计划基础研究项目，2025.1.1-2027.12.31

4. 横向：名贵海水鱼类新种质创制及产业化应用（220万），2024. 4.20-2027. 5. 31

5. 成果转化项目：

(1)膨腹海马生长关联SNP位点的单倍型在育种中的应用（5万），2024.9.19-2025.10.01

(2)膨腹海马体重关联SNP位点的双倍型在育种中的应用（5万），2024.9.27-2025.10.01

6. 鲁东大学科研启动经费：海马速生品系创制及主效基因挖掘，2024.1-2027.12

  参与项目

国家自然科学基金面上项目：海马免疫响应苯并芘胁迫的权衡策略及性二态产生的分子机制（42276118）。山东省重点研发计划（农业良种工程）：海马新种质创制及产业化应用（2023LZGCQY016）。团头鲂浦江2号新品种的研制和推广利用；团头鲂良种繁育推广；蓝色粮仓-抗多子小瓜虫和鲤疱疹病毒II型植物源小分子药物研发；蓝色粮仓-抗草鱼出血病EGCG药物开发及应用。

参与团头鲂新品种选育工作，培育国家新品种团头鲂“浦江2号”（GS01-002-2020）

　　发表论文

1. Jia, L.-W., Zhang, L.-L., Yang, H.-W., Hou, C.-Y., Shi, L., Hou, Y.-P., Zheng, G.-D., Su, X.-L.*, Wang, K., 2025. The hypoxia adaptation strategy of the big-belly seahorses (Hippocampus abdominalis) with tuft gills. Aquacult Rep 40

2. Zhang, L., Wang, F., Lv, C., Yu, L., Ci, X., Zhang, N., Jia, L., Xue, Y., Zhang, X., Su, X. *, Wang, K., 2024. Identification of CTNNB1 in the lined seahorse, Hippocampus erectus, and its function in innate immunity and cell proliferation. J World Aquaculture Soc.

3. Su, X.-L., Zheng, G.-D., Zou, S.-M., 2024b. Knockout of EPO gene in blunt snout bream (Megalobrama amblycephala) by CRISPR/Cas9 reveals its roles in hypoxia-tolerance. Aquaculture 592

4. Su, X.-L., Hou, C.-Y., Zheng, G.-D., Zou, S.-M., 2024a. Evaluation of muscle nutritional value and flavor quality between triploid and diploid blunt snout bream (Megalobrama amblycephala): Applications of breeding improvement in fish quality. Aquacult Rep 39.

5. Jia, L., Zhang, L., Yang, H., Li, L., Zheng, S., Ma, Y., Xue, Y., Zhang, J., Li, M., Su, X., Wang, K., 2024. Host-intestinal microbiota interactions in Edwardsiella piscicida-induced lethal enteritis in big-belly seahorses: Novel insights into the role of Carbohydrate-Active enzymes and host transcriptional responses. Fish Shellfish Immunol 156, 110024.

6. Wang, K., Xue, Y., Liu, Y., Su, X., Wei, L., Lv, C., Zhang, X., Zhang, L., Jia, L., Zheng, S., Ma, Y., Yan, H., Jiang, G., Song, H., Wang, F., Lin, Q., Hou, Y., 2024. The detoxification ability of sex-role reversed seahorses determines the sexual dimorphism in immune responses to benzo[a]pyrene exposure. Sci Total Environ, 173088.

7. Zhao, S.S., Su, X.L., Yang, H.Q., Zheng, G.D., Zou, S.M., 2023. Functional exploration of SNP mutations in HIF2a gene correlated with hypoxia tolerance in blunt snout bream (Megalobrama amblycephala). Fish Physiol Biochem 49(2), 239-251.

8. Shuang, L., Chen, S.L., Ren, C., Su, X.L., Xu, X.N., Zheng, G.D., Zou, S.M., 2023. Effects of hypoxia and reoxygenation on oxidative stress, histological structure, and apoptosis in a new hypoxia-tolerant variety of blunt snout bream (Megalobrama amblycephala). Comp Biochem Physiol A Mol Integr Physiol 278, 111358.

9. Tian, Y., Wang, F., Su, X., Zhang, L., Ma, Z., Gao, L., Yan, H., Xue, Y., Lv, C., Zhang, X., Li, M., Hou, Y., Wang, K., 2023. Supplementation with Enterococcus faecium enhances growth performance, intestinal health and immunity of big-belly seahorses (Hippocampus abdominalis) during diet conversion. Aquacult Rep 28.

10. Guodong Zheng, Baoyu Li, Huiqi Yang, Xiaolei Su, Chengyu Jia, Wendi Xu, Shuming Zou. 2023. Induction of high triploid rate blunt snout bream (Megalobrama amblycephala) by hydrostatic pressure and analysis of gonadal sterility mechanism. Aquaculture 563.

11. Zhang, L., Wang, F., Jia, L., Yan, H., Gao, L., Tian, Y., Su, X., Zhang, X., Lv, C., Ma, Z., Xue, Y., Lin, Q., Wang, K., 2023. Edwardsiella piscicida infection reshapes the intestinal microbiome and metabolome of big-belly seahorses: mechanistic insights of synergistic actions of virulence factors. Front Immunol 14, 1135588.

12. Xiao-Lei Su, Shan-shan Zhao, Wen-Jing Xu, Liang Shuang, Guo-Dong Zheng, Shu-Ming Zou. 2022. Efficiently whole-genomic mutagenesis approach by ARTP in blunt snout bream (Megalobrama amblycephala). Aquaculture 555,738241.

13. Xiao-Lei Su, Xin-Lin, Shan-shan Zhao, Guo-Dong Zheng, Shu-Ming Zou. 2022. Short-term starvation in Megalobrama amblycephala♀× (M. amblycephala♀×Culter alburnus♂) ♂: Effect on the histology, essential nutrients and flavor components. Aquaculture Research 53(6):2071-2080

14. Zhao, S. S., Su, X. L., Pan, R. J., Lu, L. Q., Zheng, G. D., & Zou, S. M. 2022. The transcriptomic responses of blunt snout bream (Megalobrama amblycephala) to acute hypoxia stress alone, and in combination with bortezomib. BMC Genomics 23(1):162.

15. Shuang Liang, Su Xiao-lei, Zheng Guo-dong, Zou Shu-ming. 2022. Effects of hypoxia and reoxygenation on gill remodeling, apoptosis, and oxidative stress in hypoxia-tolerant new variety blunt snout bream (Megalobrama amblycephala). Fish Physiol Biochem 48(1):263–274

16. 林欣;郑国栋;苏晓磊;陈杰;邹曙明. 2022. 黑麦草与配合饲料对鲂鲌杂交种生长、消化及鱼肉品质的影响.水产科学

17. Guodong Zheng, Xiaolei Su, Wendi Xu, Wentao Cui, Shuming Zou. 2020. Optimal dietary protein requirement of juvenile backcross variety, Megalobrama amblycephala ♀× (M. amblycephala♀×Culter alburnus♂)♂. Aquaculture Research 00:1-10.

18. 崔文涛;郑国栋;苏晓磊;李宝玉;陈杰;邹曙明. 2020. 鲂鲌杂交及回交F2群体的微卫星遗传结构及其生长性能分析.中国水产科学

19. 苏晓磊,郑国栋,蒋霞云,邹曙明. 2019.三角鲂×翘嘴鲌、团头鲂×翘嘴鲌两种杂交后代微卫星遗传结构分析.水生生物学报

20. 王东东;邹曙明;郑国栋;吴成宾;苏晓磊;崔文涛. 2019. 团头鲂耐低氧F4代和“浦江1号”1、2龄鱼生长速度比较.水产科技情报

　　专利

1. 膨腹海马生长关联SNP位点的单倍型在育种中的应用. 苏晓磊;王凯;马溢聪;侯玉平;贾龙武;董杰;林强;王信;秦耿.2024

2. 膨腹海马体重关联SNP位点的双倍型在育种中的应用. 苏晓磊;王凯;张宁;侯玉平;贾龙武;董杰;林强;王信;秦耿.2024

3. 膨腹海马吻宽关联SNP位点的双倍型在育种中的应用. 苏晓磊;王凯;贾龙武;张宁;侯玉平;石琳;林强;王信;秦耿.2024

4. 膨腹海马体长关联SNP位点的双倍型在育种中的应用. 苏晓磊;王凯;俞兰良;贾龙武;慈小静;侯玉平;林强;王信;秦耿.2024

5. 一种与团头鲂生长性状相关的分子标记及其应用. 邹曙明;苏晓磊;郑国栋.2023

6. 一种与团头鲂耐低氧性状相关的分子标记及其应用. 邹曙明;苏晓磊;郑国栋.2023

7. ELOVL1基因及其应用. 邹曙明;郑国栋;陈杰;吴成宾;苏晓磊;郭丹丹.2019

8. ELOVL6基因及其应用. 邹曙明;郑国栋;陈杰;吴成宾;苏晓磊;郭丹丹.2019

9. 一种团头鲂的耐低氧育种方法. 邹曙明;郑国栋;李福贵;陈杰;吴成宾;苏晓磊.2019

指导学生

1. 中国研究生乡村振兴科技强农+创新大赛第四届科技作品竞赛自然科学类全国二等奖（2024），指导教师

2. “建行杯”山东省大学生创新大赛山东省铜奖（2024），指导教师

3. 第四届全国大学生生命科学竞赛一等奖（2020）

　　电子邮箱

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